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编 号:F762785
分子式:C23H18ClN3O4S
分子量:467.92
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生物活性:
VEGFR-2-IN-15 (Compound 14b) is a potent VEGFR-2 inhibitor. VEGFR-2-IN-15 arrests the HepG2 cell growth at the Pre-G1 phase and induces apoptosis.

体外研究:
VEGFR-2-IN-15 (Compound 14b) shows cytotoxic activities with IC50 values of 4.754?±?0.21 μM and 4.61?±?0.34 μM against MCF-7 and HepG2 cells, respectively.VEGFR-2-IN-15 shows the highest activities with VEGFR-2 protein concentrations of 705.7?pg/ml.
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