产品
编 号：F762772
分子式：C19H11NO5S2
分子量：397.42
分子式：C19H11NO5S2
分子量：397.42
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规格
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结构图
CAS No: 3033040-76-2
产品详情
生物活性：
hCAIX/XII-IN-1 is a potent CAIX/XII inhibitor with the KI values of 0.48 μM and 0.83 μM for CAIX and CAXII, respectively. hCAIX/XII-IN-1 shows antiproliferative activity in vitro. hCAIX/XII-IN-1 induces apoptosis in MCF-7 cells.
体外研究：
hCAIX/XII-IN-1 (compound 11a) (3.125, 6.25, 12.5, 25, 50 μM, 48 h) shows antiproliferative activity with an IC50 value of 0.48 μM in MCF-7 cells.hCAIX/XII-IN-1 (0.48 μM; 24 h) increases the cell populations of Sub-G1 phase.hCAIX/XII-IN-1 (0.48 μM) induces apoptosis in MCF-7 cells.
hCAIX/XII-IN-1 is a potent CAIX/XII inhibitor with the KI values of 0.48 μM and 0.83 μM for CAIX and CAXII, respectively. hCAIX/XII-IN-1 shows antiproliferative activity in vitro. hCAIX/XII-IN-1 induces apoptosis in MCF-7 cells.
体外研究：
hCAIX/XII-IN-1 (compound 11a) (3.125, 6.25, 12.5, 25, 50 μM, 48 h) shows antiproliferative activity with an IC50 value of 0.48 μM in MCF-7 cells.hCAIX/XII-IN-1 (0.48 μM; 24 h) increases the cell populations of Sub-G1 phase.hCAIX/XII-IN-1 (0.48 μM) induces apoptosis in MCF-7 cells.
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