产品
编 号：F762765
分子式：C43H62N16
分子量：803.06
分子式：C43H62N16
分子量：803.06
产品类型
规格
价格
是否有货
结构图
CAS No: 2978694-25-4
产品详情
生物活性：
Antimicrobial agent-9 (Compound 16) is an antimicrobial agent with an MIC range of 4-8 μg/mL against gram-positive and gram-negative bacteria. Antimicrobial agent-9 also shows anti-inflammatory activity.
体外研究：
Antimicrobial agent-9 (Compound 16) (0-256 μg/mL; 18-24 h) shows antibacterial activity with geometric mean (GM) values of the MICs of 4.5 μg/mL.Antimicrobial agent-9 shows minimum hemolytic concentration (MHC) of >256 μg/mL, the therapeutic index is 113.8.Antimicrobial agent-9 (5 or 20 μg/mL; 18 h) effectively inhibits the release and expression of NO and TNF-α from LPS-stimulated RAW 264.7 cells.Antimicrobial agent-9 is resistant to various physiological salts, human serum, and proteases.Antimicrobial agent-9 exhibits synergistic antimicrobial activity in combination with three conventional antibiotics (Chloramphenicol (HY-B0239), Ciprofloxacin (HY-B0356), and oxacillin) against MDRPA and MRSA, is promising adjuvants in combination with clinically used antibiotics.
Antimicrobial agent-9 (Compound 16) is an antimicrobial agent with an MIC range of 4-8 μg/mL against gram-positive and gram-negative bacteria. Antimicrobial agent-9 also shows anti-inflammatory activity.
体外研究：
Antimicrobial agent-9 (Compound 16) (0-256 μg/mL; 18-24 h) shows antibacterial activity with geometric mean (GM) values of the MICs of 4.5 μg/mL.Antimicrobial agent-9 shows minimum hemolytic concentration (MHC) of >256 μg/mL, the therapeutic index is 113.8.Antimicrobial agent-9 (5 or 20 μg/mL; 18 h) effectively inhibits the release and expression of NO and TNF-α from LPS-stimulated RAW 264.7 cells.Antimicrobial agent-9 is resistant to various physiological salts, human serum, and proteases.Antimicrobial agent-9 exhibits synergistic antimicrobial activity in combination with three conventional antibiotics (Chloramphenicol (HY-B0239), Ciprofloxacin (HY-B0356), and oxacillin) against MDRPA and MRSA, is promising adjuvants in combination with clinically used antibiotics.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备