产品
编 号：F762756
分子式：C18H20ClN3OS
分子量：361.89
分子式：C18H20ClN3OS
分子量：361.89
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CAS No: 2982271-63-4
产品详情
生物活性：
PqsR-IN-2 (Compound 19) is a potent PqsR (Pseudomonas aeruginosa quorum sensing transcriptional regulator) inhibitor. PqsR-IN-1 attenuates pyocyanin production and has very low cytotoxicity.
体外研究：
PqsR-IN-2 (Compound 19) inhibits pqs system with IC50 values of 298 ± 182.0 nM and 265 ± 3.4 nM against two different PA strains PAO1-L and PA14, respectively.PqsR-IN-2 significantly reduces pyocyanin production to 36% against a control of 0.1% DMSO at 3 × the IC50 value in P. aeruginosa strain PAO1-L. PqsR-IN-2 (0-100 μM, 16 h) shows no significant toxicity to A549 cells.
PqsR-IN-2 (Compound 19) is a potent PqsR (Pseudomonas aeruginosa quorum sensing transcriptional regulator) inhibitor. PqsR-IN-1 attenuates pyocyanin production and has very low cytotoxicity.
体外研究：
PqsR-IN-2 (Compound 19) inhibits pqs system with IC50 values of 298 ± 182.0 nM and 265 ± 3.4 nM against two different PA strains PAO1-L and PA14, respectively.PqsR-IN-2 significantly reduces pyocyanin production to 36% against a control of 0.1% DMSO at 3 × the IC50 value in P. aeruginosa strain PAO1-L. PqsR-IN-2 (0-100 μM, 16 h) shows no significant toxicity to A549 cells.
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