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编 号:F762705
分子式:C22H26N4O7
分子量:458.46
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生物活性:
CK2-IN-3 is a selective and potent CK2 inhibitor (Kd: 12 nM), with IC50 values of 1.51 μM (CK2α) and 7.64 μM (CK2α’). CK2-IN-3 can be used in the research of cancers.

体外研究:
CK2-IN-3 (compound 31, 1 nM-100 μM) inhibits CK2 activities in permeabilized cells, with IC50 values of 8 nM (CK2α) and 38 nM (CK2α’).CK2-IN-3 (10 μM, 48 h) shows no significant cytotoxicity across 60 cancer cell lines.
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