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编 号:F084981
分子式:C58H80N16O14
分子量:1225.36
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生物活性:
TAK-448 (MVT-602) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM.

体内研究:
TAK-448 (0.01-3 mg/kg; given i.h.; dosings on day 0 and 28) has greater anti-tumor effects in VCaP xenograft model.Animal Model:Rat VCaP xenograft androgen-sensitive prostate cancer model (7-week-old rats)
Dosage:0.01, 0.03, 0.3, 3 mg/kg
Administration:Given i.h.; dosings on day 0 and 28
Result:Had greater anti-tumor effects in VCaP xenograft model.
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