产品
编 号：F762664
分子式：C8H14O9P2
分子量：316.14
分子式：C8H14O9P2
分子量：316.14
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 2930564-26-2
产品详情
生物活性：
L-690330 hydrate is a competitive inhibitor of inositol monophosphatase (IMPase) with Kis of 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase, respectively. L-690330 hydrate exhibits 10-fold more sensitive than mouse and rat IMPase.
体内研究：
L-690330 hydrate (intracerebroventricular?injection; 0.1 μmol) has no effects on their motor activity and coordination in the beam walking, except a reduction in time spent in light in the dark/light test.Animal Model:Eight-week-old male ICR mice
Dosage:0.1 μmol
Administration:Intracerebroventricular?injection
Result:Did not effect mice well-being by i.c.v injection.
体外研究：
L-690330 hydrate (50 μM; 1 hour) induces P-AMPK and autophagy and increases LC3-I/II and p-AMPK expression in HEK293 cells.
L-690330 hydrate is a competitive inhibitor of inositol monophosphatase (IMPase) with Kis of 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase, respectively. L-690330 hydrate exhibits 10-fold more sensitive than mouse and rat IMPase.
体内研究：
L-690330 hydrate (intracerebroventricular?injection; 0.1 μmol) has no effects on their motor activity and coordination in the beam walking, except a reduction in time spent in light in the dark/light test.Animal Model:Eight-week-old male ICR mice
Dosage:0.1 μmol
Administration:Intracerebroventricular?injection
Result:Did not effect mice well-being by i.c.v injection.
体外研究：
L-690330 hydrate (50 μM; 1 hour) induces P-AMPK and autophagy and increases LC3-I/II and p-AMPK expression in HEK293 cells.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备