产品
编 号:F762663
分子式:C12H12N4O2S2
分子量:308.38
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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生物活性:
TMX-4113 is a degrader of phosphodiesterase 6D (PDE6D) and casein kinase 1α (CK1α). TMX-4113 can be used for the research of cancer.

体外研究:
TMX-4113 (compound 21; 1 μM; 4 h) shows a high degradation preference for PDE6D and CK1α in MOLT4 cells.TMX-4113 (0 nM, 40 nM, 200 nM, 1μM; 4h) induces degradation of PDE6D in MOLT4 cells.TMX-4113 (0 nM, 40 nM, 200 nM, 1μM; 4h) degrades over 50% of CK1α at a dose of 40 nM in MM.1S cells.
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