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编 号:F762646
分子式:C28H24F3N5O4
分子量:551.52
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结构图
CAS No: 2968419-65-8
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生物活性:
EGFR-IN-81 (Compound 10i) is an EGFR inhibitor. EGFR-IN-81 inhibits EGFR WT and L858R/T790M with IC50s 4.38 nM and 5.69 nM. EGFR-IN-81 has cytotoxic activity against MCF-7 and HCT116 cells with of 2.07 μM and 6.72 μM respectively.