产品
编 号：F762645
分子式：C33H35BrN4O7
分子量：679.56
分子式：C33H35BrN4O7
分子量：679.56
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规格
价格
是否有货
结构图
CAS No: 2958641-42-2
产品详情
生物活性：
NDBM is a probe and binds to tumor-specific Pim-1 kinase, releases strong fluorescence, and produces cytotoxicity, thus achieving cell screening and killing effects. NDBM can specifically target lysosomes and sensitively respond to pH. NDBM can be used to track the pH changes in the intracellular environment under conditions of autophagy and external stimulation.
体内研究：
NDBM 在正常细胞 (HUVEC、RAW 264.7细胞系) 中的荧光强度低于肿瘤细胞 (MGC-803、HepG2 和Hela 细胞系) 。NDBM (2.5、5、10和20 μM, 18 h) 降低肿瘤细胞 (MGC-803、HepG 2和 Hela) 的存活率。
NDBM is a probe and binds to tumor-specific Pim-1 kinase, releases strong fluorescence, and produces cytotoxicity, thus achieving cell screening and killing effects. NDBM can specifically target lysosomes and sensitively respond to pH. NDBM can be used to track the pH changes in the intracellular environment under conditions of autophagy and external stimulation.
体内研究：
NDBM 在正常细胞 (HUVEC、RAW 264.7细胞系) 中的荧光强度低于肿瘤细胞 (MGC-803、HepG2 和Hela 细胞系) 。NDBM (2.5、5、10和20 μM, 18 h) 降低肿瘤细胞 (MGC-803、HepG 2和 Hela) 的存活率。
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