产品
编 号:F762586
分子式:C22H15ClN4O3S
分子量:450.9
产品类型
结构图
CAS No: 3017162-04-5
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产品详情
生物活性:
VEGFR-2/c-Met-IN-2 (compound 3e) is a VEGFR-2/c-Met inhibitor, with IC50 values of 83 and 48 nM, respectively. VEGFR-2/c-Met-IN-2 exhibits cytotoxic activity against HCT-116 cell line (IC50: 3.403 μM).
体外研究:
VEGFR-2/c-Met-IN-2 (compound 3e) 对结直肠癌细胞的选择性细胞毒性是正常细胞的 3 倍以上。