产品
编 号：F762568
分子式：C28H33F3N2O3
分子量：502.57
分子式：C28H33F3N2O3
分子量：502.57
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 3010910-40-1
产品详情
生物活性：
RXR antagonist 1 (compound 6a) is a retinoid X receptor (RXR) modulator. RXR antagonist 1 shows potent RXR-antagonistic activity, with a pA2 of 8.06. RXR antagonist 1 can be used for type 2 diabetes research.
体外研究：
RXR antagonist 1 (compound 6a) shows potent RXR-antagonistic activities at 1 μM.RXR antagonist 1 shows competitive binding to the LBP in hRXRα-LBD, with Ki of 0.384 ± 0.072, Kd of 0.277 ± 0.038, and Ki/Kd of 1.39.The cell permeability of RXR antagonist 1 shows no correlation with RXR-antagonistic activity.
RXR antagonist 1 (compound 6a) is a retinoid X receptor (RXR) modulator. RXR antagonist 1 shows potent RXR-antagonistic activity, with a pA2 of 8.06. RXR antagonist 1 can be used for type 2 diabetes research.
体外研究：
RXR antagonist 1 (compound 6a) shows potent RXR-antagonistic activities at 1 μM.RXR antagonist 1 shows competitive binding to the LBP in hRXRα-LBD, with Ki of 0.384 ± 0.072, Kd of 0.277 ± 0.038, and Ki/Kd of 1.39.The cell permeability of RXR antagonist 1 shows no correlation with RXR-antagonistic activity.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备