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编 号:F762563
分子式:C24H21N3O5S
分子量:463.51
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生物活性:
NS2B/NS3-IN-2 is a potent dengue virus (DENV) NS2B/NS3 covalent inhibitor with an IC50 of 6.0 nM and Ki of 0.66 μM. NS2B/NS3-IN-2 shows no cytotoxicity and markedly increases the cell survival rate.

体外研究:
NS2B/NS3-IN-2 (compound 23) (150 nM) shows 100% inhibition rate against Dengue virus (DENV).NS2B/NS3-IN-2(5 μM) shows no cytotoxicity and markedly increases the cell survival rate.
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