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编 号：F762538
分子式：C16H13F6NO2
分子量：365.27
分子式：C16H13F6NO2
分子量：365.27
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CAS No: 2987139-96-6
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生物活性：
IAA65 is a potent T-type calcium channel inhibitor with a IC50 value of 18.9 μM. IAA65 can be used for epilepsy research.
体外研究：
IAA65 (50 μM; differentiated ND7/23 cells) causes a significant reduction in the current density generated by T-type Ca2+ channel activation.IAA65 (50 μM; differentiated ND7/23 cells) alters the steady-state inactivation of Cav3.2 and Cav3.3 T-type Ca2+ channels, which resulted in a significant increase in the inactivation recovery time of the channels.
IAA65 is a potent T-type calcium channel inhibitor with a IC50 value of 18.9 μM. IAA65 can be used for epilepsy research.
体外研究：
IAA65 (50 μM; differentiated ND7/23 cells) causes a significant reduction in the current density generated by T-type Ca2+ channel activation.IAA65 (50 μM; differentiated ND7/23 cells) alters the steady-state inactivation of Cav3.2 and Cav3.3 T-type Ca2+ channels, which resulted in a significant increase in the inactivation recovery time of the channels.
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