产品
编 号：F762532
分子式：C28H27FN2O3
分子量：458.52
分子式：C28H27FN2O3
分子量：458.52
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 2988135-14-2
产品详情
生物活性：
FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with KD values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research.
体内研究：
MF 6 (1 mg/kg; i.g.; daily for 4 weeks) improves the severity of EAE (experimental autoimmune encephalomyelitis) and attenuates oxidative levels and the inflammatory response.Animal Model:8-10-week-old female C57BMF/6J mice with MOG35-55-administered experimental autoimmune encephalomyelitis (EAE) mouse model
Dosage:1 mg/kg
Administration:Intragastric administration, daily for 4 weeks
Result:Attenuated EAE symptoms, decreased oxidative stress, inhibited astrocyte activation and protected oligodendrocytes.
体外研究：
FABPs ligand 6 (MF6) rescues mitochondrial function by blocking voltagedependent anion channel (VDAC)-1-dependent mitochondrial macropore formation induced by psychosine in KG-1C cells, a FABP5- mediated injury.
FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with KD values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research.
体内研究：
MF 6 (1 mg/kg; i.g.; daily for 4 weeks) improves the severity of EAE (experimental autoimmune encephalomyelitis) and attenuates oxidative levels and the inflammatory response.Animal Model:8-10-week-old female C57BMF/6J mice with MOG35-55-administered experimental autoimmune encephalomyelitis (EAE) mouse model
Dosage:1 mg/kg
Administration:Intragastric administration, daily for 4 weeks
Result:Attenuated EAE symptoms, decreased oxidative stress, inhibited astrocyte activation and protected oligodendrocytes.
体外研究：
FABPs ligand 6 (MF6) rescues mitochondrial function by blocking voltagedependent anion channel (VDAC)-1-dependent mitochondrial macropore formation induced by psychosine in KG-1C cells, a FABP5- mediated injury.
产品资料
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