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编 号:F762463
分子式:C16H22ClNOS
分子量:311.87
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生物活性:
Anti-Influenza agent 3 (compound 11h) is a potent anti-influenza agent with EC50 values of 3.29, 2.45 μM for A/HK/68 (H3N2, M2-WT), A/WSN/33 (H1N1, M2-S31N) strain, respectively. Anti-Influenza agent 3 shows low cytotoxicity for MDCK epithelial cells. Anti-Influenza agent 3 inhibits the M2 WT and S31N ion channel conductivity.

体外研究:
Anti-Influenza agent 3 shows lowe cytotoxicity for MDCK epithelial cells with an TC50 of >173.14 μM.Anti-Influenza agent 3 (100 μM) inhibits the M2 WT and S31N ion channel conductivity in 293 T-Rex cells.
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