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编 号:F762374
分子式:C19H28O5
分子量:336.42
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1mg
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5mg
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10mg
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25mg
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50mg
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生物活性:
3,4,5-Trihydroxycinnamic acid decyl ester is an excellent inhibitor of lipid absorption and accumulation, with anti-obesity properties. 3,4,5-Trihydroxycinnamic acid decyl ester is a pancreatic lipase inhibitor, with an EC50 of approximately 0.9 μM.

体内研究:
3,4,5-Trihydroxycinnamic acid decyl ester (30-150 mg/kg; p.o.) suppresses a rise in blood triglyceride (TG) levels in mice given corn oil orally.Animal Model:6 weeks old Male ddY mice
Dosage:30 mg/kg, 150 mg/kg
Administration:Oral administration
Result:Reduced plasma TG in a dose-dependent manner.

体外研究:
3,4,5-Trihydroxycinnamic acid decyl ester (30 μM) exhibits an inhibitory potency of approximately 92% for pancreatic lipase in vitro.3,4,5-Trihydroxycinnamic acid decyl ester (0.1-40 μM) inhibits pancreatic lipase activity in dose-dependent manner, with an EC50 value being approximately 0.9 μM.3,4,5-Trihydroxycinnamic acid decyl ester inhibits pancreatic lipase in vitro and lipid accumulation during 3T3-L1 cell differentiation.
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