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编 号:F762321
分子式:C19H14F4N4OS
分子量:422.4
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CAS No: 259089-67-3
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体外研究:
SEW84 (5 μM) shows complete inhibition of ASH activity with an IC50 value of 0.3 μM.SEW84 inhibited the GR- and AR-dependent luciferase expression with IC50 values of 1.3 and 0.7 μM, respectively.SEW84 (0-20 μM) inhibits the Hsp90-Dependent folding of firefly luciferase.SEW84 (0, 3, 10, 30 μM; 24 h) specifically clears phosphorylated tau.