产品
编 号:F084508
分子式:C31H23NO6
分子量:505.52
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10mM*1mL in DMSO
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2mg
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5mg
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10mg
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生物活性:
Ampkinone is an indirect AMP-activated protein kinase (AMPK) activator.

体内研究:
Ampkinone-treated DIO mice significantly reduce total body weight and overall fat mass. Histological examination and measurement of lipid parameters show that Ampkinone effectively improves metabolic abnormalities in the DIO mice model.

体外研究:
Ampkinone stimulates the phosphorylation of AMPK via the indirect activation of AMPK in various cell lines. Ampkinone-mediated activation of AMPK requires the activity of LKB1 and results in increased glucose uptake inmuscle cells.
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