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编 号:F762096
分子式:C38H60O12
分子量:708.88
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10mM*1mL in DMSO
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5mg
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10mg
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生物活性:
Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis.

体内研究:
Enfumafungin (50 -200 mg/kg;ip 每天两次,持续 2 天) 减少小鼠肾脏中 C.albicans 的菌落数,ED90 为 90 mg/kg。

体外研究:
Enfumafungin(24-48 小时)对 Candida 和 Aspergillus 的 MIC 小于 0.5 μg/mL。
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