产品
编 号:F761856
分子式:C23H23NO2
分子量:345.43
产品类型
结构图
CAS No: 96389-68-3
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产品详情
生物活性:
Crisnatol (BWA770U) is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts.
体内研究:
Crisnatol (25 mg/kg; p.o.; single dose) 显示出口服活性,并通过放射自显影显示大鼠粪便提取物的稳定代谢物谱。
体外研究:
Crisnatol (1.3 μg/mL; 24-72 h) 抑制 HepG2 细胞的复制,使细胞活力降低 35%。