产品
编 号：F761826
分子式：C19H21ClN4O2S2
分子量：436.98
分子式：C19H21ClN4O2S2
分子量：436.98
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CAS No: 958941-60-1
产品详情
生物活性：
CFTR corrector 12 (compound 17C) is a bithiazole derivative, serving as CFTR corrector. CFTR corrector 12 has the ability to correct some folding defective mutants of the channel responsible for the control of chloride transport across the plasma membrane. CFTR corrector 12 recovers the α-sarcoglycan (α-SG) content in mutant cells.
体外研究：
CFTR corrector 12 (compound 17C) (15 μM; 72 h) 能够恢复 L31P/V247M α-SG 突变细胞中 α-肌聚糖含量。
CFTR corrector 12 (compound 17C) is a bithiazole derivative, serving as CFTR corrector. CFTR corrector 12 has the ability to correct some folding defective mutants of the channel responsible for the control of chloride transport across the plasma membrane. CFTR corrector 12 recovers the α-sarcoglycan (α-SG) content in mutant cells.
体外研究：
CFTR corrector 12 (compound 17C) (15 μM; 72 h) 能够恢复 L31P/V247M α-SG 突变细胞中 α-肌聚糖含量。
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