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编 号:F761799
分子式:C56H93N21O19
分子量:1364.47
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生物活性:
Presenilin 1 (349-361) is an active petide, and synthetic peptides representing amino acids 349–361 can be phosphorylated by glycogen synthase kinase-3β(GSK3β) in vitro. Presenilin 1 (349-361) can be used for the research of various diseases.

体外研究:
Presenilin 1 (349-361) reduces the interaction with beta-catenin leading to decreased phosphorylation and ubiquitination of beta-catenin when structural change, thereby increases its nuclear signaling and the transcription of target genes, including c-MYC.
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