产品
编 号:F761703
分子式:C28H34N6O5
分子量:534.61
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5mg
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10mg
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25mg
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生物活性:
Macimorelin (EP-1572) acetate, a GH secretagogue, is an orally active GHSR agonist. Macimorelin acetate stimulates GH release. Macimorelin acetate can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS).

体内研究:
Macimorelin 醋酸酯 (5mg/kg,每日两次,连续 2 周) 可降低 IHKA 小鼠模型的癫痫发作次数和持续时间。Animal Model:Intrahippocampal kainic acid (IHKA) mouse model
Dosage:5 mg/kg
Administration:Intraperitoneal injection (i.p.), twice daily for 2 weeks.
Result:Significantly decreased the number and duration of seizures during the treatment period, but had no antiepileptogenic or disease-modifying effect.
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