产品
编 号：F761672
分子式：C10H10N4O2S
分子量：250.28
分子式：C10H10N4O2S
分子量：250.28
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
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5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 943119-42-4
产品详情
生物活性：
OUL232 is a potent inhibitor of mono-ARTs PARP7, PARP10, PARP11, PARP12, PARP14, and PARP15. OUL232 is the most potent PARP10 inhibitor described to date (IC50=7.8 nM), as well as the first PARP12 inhibitor ever reported.
体外研究：
OUL232 (化合物 27) (1 μM; 10-12 d) 拯救过表达 PARP10 的细胞，使其免于 ADP 核糖化依赖的细胞死亡。药代动力学分析water solubility μg/mLGI Papp×10-6 cm/s (RM %)BBB Papp×10-6 cm/s (RM %)metabolic stablity %stab in human plasmastab. in MeOHstab in PBS pH 7.4
12.600.1440.14399.11>24>24>24
OUL232 is a potent inhibitor of mono-ARTs PARP7, PARP10, PARP11, PARP12, PARP14, and PARP15. OUL232 is the most potent PARP10 inhibitor described to date (IC50=7.8 nM), as well as the first PARP12 inhibitor ever reported.
体外研究：
OUL232 (化合物 27) (1 μM; 10-12 d) 拯救过表达 PARP10 的细胞，使其免于 ADP 核糖化依赖的细胞死亡。药代动力学分析water solubility μg/mLGI Papp×10-6 cm/s (RM %)BBB Papp×10-6 cm/s (RM %)metabolic stablity %stab in human plasmastab. in MeOHstab in PBS pH 7.4
12.600.1440.14399.11>24>24>24
产品资料
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