产品
编 号：F761649
分子式：C26H29N3O4
分子量：447.53
分子式：C26H29N3O4
分子量：447.53
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CAS No: 939769-93-4
产品详情
生物活性：
K34c is a potent and selective α5β1 integrin antagonist. K34c can be used for glioblastoma research.
体外研究：
K34c (20 μM; 24 or 48 h) significantly induces U87MG cells apoptosis in combination with 1 μM Ellipticine (HY-15753).K34c (20 μM; 48 h) decreases significantly Temozolomide (HY-17364)-induced senescence in cells transfected with control non targeting siRNA without affecting significantly the residual senescence of cells transfected with siRNA specific for p53.K34c (20 μM; 24 h) modulates the p53 pathway.
K34c is a potent and selective α5β1 integrin antagonist. K34c can be used for glioblastoma research.
体外研究：
K34c (20 μM; 24 or 48 h) significantly induces U87MG cells apoptosis in combination with 1 μM Ellipticine (HY-15753).K34c (20 μM; 48 h) decreases significantly Temozolomide (HY-17364)-induced senescence in cells transfected with control non targeting siRNA without affecting significantly the residual senescence of cells transfected with siRNA specific for p53.K34c (20 μM; 24 h) modulates the p53 pathway.
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