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编 号：F761566
分子式：C30H33N3OS
分子量：483.67
分子式：C30H33N3OS
分子量：483.67
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CAS No: 93076-87-0
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生物活性：
JNJ-3790339, a Ritanserin (HY-10791) analog, is a potent and selective diacylglycerol kinase (DGKα) inhibitor with an IC50 of 9.6 μM. JNJ-3790339 has induction of toxicity in malignant cells, and improves ability to upregulate T cell activation.
体外研究：
JNJ-3790339 (5-40 μM; 48 h) exhibits cytotoxic efficacy against A375, U251 and Jurkat T.JNJ-3790339 (5 μM; 6 h) promotes activation of primary murine T cells.
JNJ-3790339, a Ritanserin (HY-10791) analog, is a potent and selective diacylglycerol kinase (DGKα) inhibitor with an IC50 of 9.6 μM. JNJ-3790339 has induction of toxicity in malignant cells, and improves ability to upregulate T cell activation.
体外研究：
JNJ-3790339 (5-40 μM; 48 h) exhibits cytotoxic efficacy against A375, U251 and Jurkat T.JNJ-3790339 (5 μM; 6 h) promotes activation of primary murine T cells.
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