产品
编 号：F761509
分子式：C16H20N2O4
分子量：304.34
分子式：C16H20N2O4
分子量：304.34
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 924835-67-6
产品详情
生物活性：
LP-184 (compound 6), an acylfulvene analog, inhibits tumor growth. LP-184 has potent anti-cancer activity in the ovarian, colon, prostate and pancreatic cell lines. (patent WO2007019308A2).
体内研究：
LP-184 (7.5 and 10 mg/kg; i.p.; 21 day) has potent 15 anti-tumor activity against MV522 tumors, producing 4/6 and 5/5 partial responses, respectively.Animal Model:Mice (MV522 tumors)
Dosage:7.5 and 10 mg/kg
Administration:I.p; 21day
Result:Effective agent for human anti-tumor therapy.
体外研究：
LP-184 inhibits the growth of HT29, OVCAR-3, AsPC-1 and PC-3, with GI50s of 0.68, 0.6, 16 and 0.14 μM, respectively.LP-184 displays IC50s of 800nM and 210 nM for anti-cancer activitie in the thymidine incorporation into cellular DNA (2 hour) and Trypan blue (48 hour) assay.
LP-184 (compound 6), an acylfulvene analog, inhibits tumor growth. LP-184 has potent anti-cancer activity in the ovarian, colon, prostate and pancreatic cell lines. (patent WO2007019308A2).
体内研究：
LP-184 (7.5 and 10 mg/kg; i.p.; 21 day) has potent 15 anti-tumor activity against MV522 tumors, producing 4/6 and 5/5 partial responses, respectively.Animal Model:Mice (MV522 tumors)
Dosage:7.5 and 10 mg/kg
Administration:I.p; 21day
Result:Effective agent for human anti-tumor therapy.
体外研究：
LP-184 inhibits the growth of HT29, OVCAR-3, AsPC-1 and PC-3, with GI50s of 0.68, 0.6, 16 and 0.14 μM, respectively.LP-184 displays IC50s of 800nM and 210 nM for anti-cancer activitie in the thymidine incorporation into cellular DNA (2 hour) and Trypan blue (48 hour) assay.
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