产品
编 号：F761395
分子式：C16H20BO2P
分子量：286.11
分子式：C16H20BO2P
分子量：286.11
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
结构图
CAS No: 914940-24-2
产品详情
生物活性：
PB2 is a tris(2-carboxyethyl)phosphine (TCEP) analogue increasing retinal ganglion (RGCs) cells survival after axotomy in vitro at nanomolar and picomolar concentrations. PB2 is substantially more permeable than TCEP. PB2, as a reducing agent, is highly neuroprotective for RGCs.
体外研究：
PB2 (0.001~100000 nM; 72 hours; RGCs) increases RGC viability.PB2 has modifications that neutralize the polarity of the compounds.The methylesters of PB2 is likely to be cleaved by cytosolic esterases, yielding a polar intracellular intermediate that would be unlikely to cross cell membranes.
PB2 is a tris(2-carboxyethyl)phosphine (TCEP) analogue increasing retinal ganglion (RGCs) cells survival after axotomy in vitro at nanomolar and picomolar concentrations. PB2 is substantially more permeable than TCEP. PB2, as a reducing agent, is highly neuroprotective for RGCs.
体外研究：
PB2 (0.001~100000 nM; 72 hours; RGCs) increases RGC viability.PB2 has modifications that neutralize the polarity of the compounds.The methylesters of PB2 is likely to be cleaved by cytosolic esterases, yielding a polar intracellular intermediate that would be unlikely to cross cell membranes.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备