产品
编 号：F761288
分子式：C18H20N2O4S
分子量：360.43
分子式：C18H20N2O4S
分子量：360.43
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 903886-95-3
产品详情
生物活性：
A-908292 is a potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor, with an IC50 of 23 nM for human ACC2. A-908292 can be used for the research of fatty acid metabolism. A-908292 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体内研究：
A-908292 (30 mg/kg; p.o.; twice a day for 2 weeks) 可降低 ob/ob 小鼠的血清葡萄糖和甘油三酯水平。A-908292 (15 mg/kg; p.o.; twice a day for 4 days) 可显着降低 ACC2 敲除小鼠的血浆甘油三酯水平。A-908292 (30-100 mg/kg; p.o.; twice a day for 3 days) 可刺激大鼠体内的 PPAR-α 依赖性信号传导通路。
A-908292 is a potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor, with an IC50 of 23 nM for human ACC2. A-908292 can be used for the research of fatty acid metabolism. A-908292 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体内研究：
A-908292 (30 mg/kg; p.o.; twice a day for 2 weeks) 可降低 ob/ob 小鼠的血清葡萄糖和甘油三酯水平。A-908292 (15 mg/kg; p.o.; twice a day for 4 days) 可显着降低 ACC2 敲除小鼠的血浆甘油三酯水平。A-908292 (30-100 mg/kg; p.o.; twice a day for 3 days) 可刺激大鼠体内的 PPAR-α 依赖性信号传导通路。
产品资料
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