产品
编 号：F761264
分子式：C16H13N3O2
分子量：279.29
分子式：C16H13N3O2
分子量：279.29
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
询价
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10mg
询价
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25mg
询价
询价
50mg
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询价
结构图
CAS No: 901599-43-7
产品详情
生物活性：
5-HT3 antagonist 5 is a quinoxalin-2-carboxamide compound, a 5-HT3 receptor antagonist. 5-HT3 antagonist 5 exerts antagonism on 5-HT3 agonist and 2-methyl-5-HT, and shows anti-depressant effect in mice.
体内研究：
5-HT3 antagonist 5 (compound 4c) (1 mg/kg; i.p.; single dose) decreases the duration of immobility and shows anti-depressant effect in FST mice.Animal Model:Swiss albino mice (23 ± 2 g)
Dosage:1 mg/kg
Administration:Intraperitoneal injection; single dose; locomotor scores tested 10 min after administration
Result:Reduced the duration of immobility as compared to the vehicle-treated (control) group.Showed no effect on the locomotion of mice as observed in spontaneous locomotor activity.
体外研究：
5-HT3 antagonist 5 (compound 4c) exhibits 5-HT3 receptor antagonisms in longitudinal muscle myenteric plexus preparation from guinea pig ileum against 5-HT3 agonist, 2-methyl-5-HT, with pA2 value of 5.
5-HT3 antagonist 5 is a quinoxalin-2-carboxamide compound, a 5-HT3 receptor antagonist. 5-HT3 antagonist 5 exerts antagonism on 5-HT3 agonist and 2-methyl-5-HT, and shows anti-depressant effect in mice.
体内研究：
5-HT3 antagonist 5 (compound 4c) (1 mg/kg; i.p.; single dose) decreases the duration of immobility and shows anti-depressant effect in FST mice.Animal Model:Swiss albino mice (23 ± 2 g)
Dosage:1 mg/kg
Administration:Intraperitoneal injection; single dose; locomotor scores tested 10 min after administration
Result:Reduced the duration of immobility as compared to the vehicle-treated (control) group.Showed no effect on the locomotion of mice as observed in spontaneous locomotor activity.
体外研究：
5-HT3 antagonist 5 (compound 4c) exhibits 5-HT3 receptor antagonisms in longitudinal muscle myenteric plexus preparation from guinea pig ileum against 5-HT3 agonist, 2-methyl-5-HT, with pA2 value of 5.
产品资料
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