产品
编 号：F083982
分子式：C21H38ClN
分子量：339.99
分子式：C21H38ClN
分子量：339.99
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
500mg
240
In-stock
结构图
CAS No: 123-03-5
产品详情
生物活性：
Cetylpyridinium chloride, a cationic quaternary ammonium compound, is an anti-bacterial agent with broad-spectrum activity. Cetylpyridinium chloride is an effective anti-HBV capsid assembly inhibitor with an IC50 of 2.5 μM. Cetylpyridinium chloride is used in pesticides and various types of mouthwashes, and other personal care products.
体内研究：
Cetylpyridinium chloride (30 μg/kg; intramuscular injection; daily; for 3 days; male C57BL/6 mice) treatment inhibits HBV replication in mouse hydrodynamic model system.Animal Model:Male C57BL/6 mice (6-week old) injected with the plasmid
Dosage:272?μg/kg/day
Administration:Intramuscular injection; daily; for 3 days
Result:Suppressed serum HBV DNA levels, decreased by 60% in day2 and 45% in day3 compared to the control.
体外研究：
Cetylpyridinium chloride interacts with dimeric viral nucleocapsid protein (known as core protein or HBcAg) specifically. Compared with other HBV inhibitors, Cetylpyridinium chloride achieves significantly better reduction of HBV particle number in HepG2.2.15 cell line. Cetylpyridinium chloride inhibits capsid assembly and leads to reduced HBV biogenesis.Cetylpyridinium chloride is a safe antimicrobial agent with broad-spectrum activity for preventing biofilm formation and gingivitis.
Cetylpyridinium chloride, a cationic quaternary ammonium compound, is an anti-bacterial agent with broad-spectrum activity. Cetylpyridinium chloride is an effective anti-HBV capsid assembly inhibitor with an IC50 of 2.5 μM. Cetylpyridinium chloride is used in pesticides and various types of mouthwashes, and other personal care products.
体内研究：
Cetylpyridinium chloride (30 μg/kg; intramuscular injection; daily; for 3 days; male C57BL/6 mice) treatment inhibits HBV replication in mouse hydrodynamic model system.Animal Model:Male C57BL/6 mice (6-week old) injected with the plasmid
Dosage:272?μg/kg/day
Administration:Intramuscular injection; daily; for 3 days
Result:Suppressed serum HBV DNA levels, decreased by 60% in day2 and 45% in day3 compared to the control.
体外研究：
Cetylpyridinium chloride interacts with dimeric viral nucleocapsid protein (known as core protein or HBcAg) specifically. Compared with other HBV inhibitors, Cetylpyridinium chloride achieves significantly better reduction of HBV particle number in HepG2.2.15 cell line. Cetylpyridinium chloride inhibits capsid assembly and leads to reduced HBV biogenesis.Cetylpyridinium chloride is a safe antimicrobial agent with broad-spectrum activity for preventing biofilm formation and gingivitis.
产品资料
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