产品
编 号：F761121
分子式：C35H48N6O8
分子量：680.79
分子式：C35H48N6O8
分子量：680.79
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
结构图
CAS No: 884650-98-0
产品详情
生物活性：
Mpro inhibitor N3 is a potent SARS-CoV-2 MPro inhibitor with an EC50 value of 16.77 μM. Mpro inhibitor N3 shows antiviral activities against HCoV-229E, FIPV, IBV and MHV-A59.
体内研究：
Mpro inhibitor N3 (0-0.64 μM; 3, 6 h) 在鸡胚胎中表现出抗 IBV 的抗病毒活性。Animal Model:Chicken embryos
Dosage:0-0.64 μM
Administration:3, 6 h with 100-EID50 titer of IBV M41 virus
Result:Showed that N3 is able to penetrate cells to inhibit the replication of IBV viruses, probably at the beginning of infection, with the PD50 of 0.13 μmol for the 3-h group and 0.17 μmol for the 6-h group.
体外研究：
Mpro inhibitor N3 (0-100 μM) 具有抗病毒活性，对 SARS-CoV-2 的 EC50 值为 16.77 μM。Mpro inhibitor N3 (0-50 μM; 14 h) 抑制病毒生长，对 HCoV-229E、FIPV 和 MHV-A59 的 IC50 值分别为 4、8.8、2.7 μM。
Mpro inhibitor N3 is a potent SARS-CoV-2 MPro inhibitor with an EC50 value of 16.77 μM. Mpro inhibitor N3 shows antiviral activities against HCoV-229E, FIPV, IBV and MHV-A59.
体内研究：
Mpro inhibitor N3 (0-0.64 μM; 3, 6 h) 在鸡胚胎中表现出抗 IBV 的抗病毒活性。Animal Model:Chicken embryos
Dosage:0-0.64 μM
Administration:3, 6 h with 100-EID50 titer of IBV M41 virus
Result:Showed that N3 is able to penetrate cells to inhibit the replication of IBV viruses, probably at the beginning of infection, with the PD50 of 0.13 μmol for the 3-h group and 0.17 μmol for the 6-h group.
体外研究：
Mpro inhibitor N3 (0-100 μM) 具有抗病毒活性，对 SARS-CoV-2 的 EC50 值为 16.77 μM。Mpro inhibitor N3 (0-50 μM; 14 h) 抑制病毒生长，对 HCoV-229E、FIPV 和 MHV-A59 的 IC50 值分别为 4、8.8、2.7 μM。
产品资料
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