产品
编 号:F761105
分子式:C32H53N9O5
分子量:643.82
产品类型
结构图
CAS No: 88280-21-1
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产品详情
生物活性:
LPLRF-NH2 is a member of RFamide peptide with anorexigenic effect. LPLRF-NH2 increases arterial blood pressure and modulates the electrical activity of brainstem neurons.
体内研究:
LPLRF-NH2 (3-15 nmol, ICV) shows anorexigenic effect in chicks.LPLRF-NH2 (25-50 nM/kg, 150 μL, i.v.) increases arterial blood pressure in rats.Animal Model:Chicks
Dosage:3.0, 7.0 or 15 nmol
Administration:Intracerebroventrical injection (ICV) injection
Result:Decreased food intake.Increased number of c-Fos reactive cells in the paraventricular nucleus.
体外研究:
YMRF-NH2 (0.1 nM-1 μM) inhibits Forskolin-induced production of cAMP in CHO cells.