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编 号：F760825
分子式：C22H23NO5
分子量：381.42
分子式：C22H23NO5
分子量：381.42
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CAS No: 861968-02-7
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生物活性：
FLDP-8 is a curcuminoid analogues, has potent anti-cancer effects. FLDP-8 can induce cell death with an IC50 value of 4 μM in LN-18 cells.
体外研究：
FLDP-8 (0-40 μM, 24 h) induces cell death process with an IC50 value of 4 μM in a concentration-dependent manner in LN-18 cells, which involves oxidative stress.FLDP-8 (1.25 μM, 2.5 μM, 24 h) induces significant S-phase cell cycle arrest.FLDP-8 (2.5 μM, 5 μM, 24 h) exhibits anti-cancer effects with anti-proliferative, anti-migratory and high potency of BBB permeable properties in Glioblastoma multiforme (GBM).
FLDP-8 is a curcuminoid analogues, has potent anti-cancer effects. FLDP-8 can induce cell death with an IC50 value of 4 μM in LN-18 cells.
体外研究：
FLDP-8 (0-40 μM, 24 h) induces cell death process with an IC50 value of 4 μM in a concentration-dependent manner in LN-18 cells, which involves oxidative stress.FLDP-8 (1.25 μM, 2.5 μM, 24 h) induces significant S-phase cell cycle arrest.FLDP-8 (2.5 μM, 5 μM, 24 h) exhibits anti-cancer effects with anti-proliferative, anti-migratory and high potency of BBB permeable properties in Glioblastoma multiforme (GBM).
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