产品
编 号：F760808
分子式：C24H26F3N5
分子量：441.49
分子式：C24H26F3N5
分子量：441.49
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规格
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是否有货
10mM*1mL in DMSO
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1mg
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5mg
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10mg
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结构图
CAS No: 859518-94-8
产品详情
生物活性：
T0467 activates parkin mitochondrial translocation in a PINK1-dependent manner in vitro. T0467 do not induce mitochondrial accumulation of PINK1in dopaminergic neurons. T0467 is a potential compound for PINK1-Parkin signaling activation, and can be used for parkinson's disease and related disorders research.
体外研究：
T0467 (2.5-20 μM; 3 hours) stimulates the mitochondrial translocation of GFP-Parkinover 12?μM in HeLa/GFP-Parkin cells. When HeLa/GFP-Parkin cells are treated with 20?μM T0467 for 3 h, GTP-Parkin is translocated to the mitochondria in approximately 21% of cells.T0467 does not show obvious toxicity in Drosophila at concentrations T0467 相关抗体:
T0467 activates parkin mitochondrial translocation in a PINK1-dependent manner in vitro. T0467 do not induce mitochondrial accumulation of PINK1in dopaminergic neurons. T0467 is a potential compound for PINK1-Parkin signaling activation, and can be used for parkinson's disease and related disorders research.
体外研究：
T0467 (2.5-20 μM; 3 hours) stimulates the mitochondrial translocation of GFP-Parkinover 12?μM in HeLa/GFP-Parkin cells. When HeLa/GFP-Parkin cells are treated with 20?μM T0467 for 3 h, GTP-Parkin is translocated to the mitochondria in approximately 21% of cells.T0467 does not show obvious toxicity in Drosophila at concentrations T0467 相关抗体:
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