产品
编 号:F760713
分子式:C23H11F2NO6
分子量:435.33
产品类型
结构图
CAS No: 852057-94-4
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产品详情
生物活性:
KMG-104 is a highly selective fluorescent Mg2+ probe. KMG-104 has been used widely and revealed Mg2+ mobilization in cytoplasm in various types of cells.
体外研究:
KMG-104 is useful for confocal laser scanning microscopy because it is excited at 490 nm, and emitted fluorescence around 510 nm. Fluorescent intensity of KMG-104 increases with [Mg] increase, and it shows no response to Na, K, and Ca; the dissociation constant (Kd) for Mg is 3 mM. KMG-104 is able to trace only [Mg] change inphysiological conditions.PC12 cells are loaded with a novel Mg indicator KMG-104 and Ca indicator fura-2, and intracellular Mg is studied in the endoplasmic reticulums (ERs), mitochondria, and Mg-ATP.