产品
编 号:F760669
分子式:C9H9Cl2F3N4
分子量:301.1
产品类型
结构图
CAS No: 849335-07-5
联系客服
产品详情
生物活性:
AC-099 hydrochloride (compound 3) is a selective NPFF2R full agonist (EC50=1189 nM) and NPFF1R partial agonist (EC50=2370 nM). AC-099 hydrochloride attenuates spinal nerve ligation-induced hypersensitivity in rats.
体内研究:
AC-099 hydrochloride (化合物 3; 30 mg/kg; i.p.; single) 完全减弱了 SNL (脊神经结扎) 诱导的大鼠超敏性。Animal Model:Male Sprague-Dawley rats (175-300g; spinal nerve ligation (SNL) model).
Dosage:30 mg/kg
Administration:Intraperitoneal injection; single.
Result:Completely attenuated SNL-induced hypersensitivity.