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编 号:F760669
分子式:C9H9Cl2F3N4
分子量:301.1
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5mg
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10mg
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50mg
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100mg
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生物活性:
AC-099 hydrochloride (compound 3) is a selective NPFF2R full agonist (EC50=1189 nM) and NPFF1R partial agonist (EC50=2370 nM). AC-099 hydrochloride attenuates spinal nerve ligation-induced hypersensitivity in rats.

体内研究:
AC-099 hydrochloride (化合物 3; 30 mg/kg; i.p.; single) 完全减弱了 SNL (脊神经结扎) 诱导的大鼠超敏性。Animal Model:Male Sprague-Dawley rats (175-300g; spinal nerve ligation (SNL) model).
Dosage:30 mg/kg
Administration:Intraperitoneal injection; single.
Result:Completely attenuated SNL-induced hypersensitivity.
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