产品
编 号:F759941
分子式:C23H30N2O7S
分子量:478.56
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5mg
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10mg
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生物活性:
YG1702 is a potent ALDH18A1-specific inhibitor. YG1702 attenuates the growth of MYCN-amplified NB and down-regulates MYCN. YG1702 physically interacts with ALDH18A1 with a high affinity and might potentially affect its enzymatic activity.

体内研究:
YG1702(腹腔注射,45 mg/kg,每3天一次,共3次)抑制荷瘤小鼠异种移植物的生长。Animal Model:NOD/SCID mice (5-6-week-old female)
Dosage:45 mg/kg
Administration:Intraperitoneal injection (I.P.), once every 3 days, three times
Result:Inhibited the growth of the xenografts in tumor-bearing mice.
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