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编 号：F759837
分子式：C35H49N10O18P
分子量：928.79
分子式：C35H49N10O18P
分子量：928.79
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CAS No: 70754-23-3
产品详情
生物活性：
Delta (Phospho) Sleep Inducing Peptide (DSIP-P) is a long-lasting sleep-promoting peptide. Delta (Phospho) Sleep Inducing Peptide induces changes in the circadian locomotor behavior in rats.
体内研究：
Delta (Phospho) Sleep Inducing Peptide (0.1 nmol/kg; i.v.; once daily for 4 times) induces changes in the circadian locomotor behavior.Delta (Phospho) Sleep Inducing Peptide (20 or 200 pmol/kg; inject into the 3rd cerebroventricle of male rats immediately before the onset of the dark period)increases slow-wave sleep and paradoxical sleep during the subsequent dark period without shortening sleep latency at a dose of 200 pmol/kg.Animal Model:Female rats from own inbred strain (KBS/K60)
Dosage:0.1 nmol/kg
Administration:Intravenous injection; once daily for 4 consecutive days
Result:Induced rapid and mark changes in the circadian locomotor behavior when during the light (sleeping) phase testing animals became relatively more active.
体外研究：
Delta (Phospho) Sleep Inducing Peptide (20-300 nM) increases rat pineal N-acetyltransferase (NAT) activity induced by norepinephrine in vitro.
Delta (Phospho) Sleep Inducing Peptide (DSIP-P) is a long-lasting sleep-promoting peptide. Delta (Phospho) Sleep Inducing Peptide induces changes in the circadian locomotor behavior in rats.
体内研究：
Delta (Phospho) Sleep Inducing Peptide (0.1 nmol/kg; i.v.; once daily for 4 times) induces changes in the circadian locomotor behavior.Delta (Phospho) Sleep Inducing Peptide (20 or 200 pmol/kg; inject into the 3rd cerebroventricle of male rats immediately before the onset of the dark period)increases slow-wave sleep and paradoxical sleep during the subsequent dark period without shortening sleep latency at a dose of 200 pmol/kg.Animal Model:Female rats from own inbred strain (KBS/K60)
Dosage:0.1 nmol/kg
Administration:Intravenous injection; once daily for 4 consecutive days
Result:Induced rapid and mark changes in the circadian locomotor behavior when during the light (sleeping) phase testing animals became relatively more active.
体外研究：
Delta (Phospho) Sleep Inducing Peptide (20-300 nM) increases rat pineal N-acetyltransferase (NAT) activity induced by norepinephrine in vitro.
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