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编 号：F759800
分子式：C16H16O6
分子量：304.29
分子式：C16H16O6
分子量：304.29
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CAS No: 700870-56-0
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生物活性：
Methyl gerfelin inhibits osteoclast differentiation by binding 3 major cellular proteins: glyoxalase 1 (GLO1), sterol binding protein 2 (SCP2), and small glutamine-rich tetratricopeptide repeat containing protein A (SGTA). Methyl gerfelin is a potent GLO1 inhibitor related to the flavonoid class.
体外研究：
Methyl gerfelin (0-30 μM; 72 h) 抑制破骨细胞形成，IC50 为 2.8 μM，有效浓度下不影响成熟破骨细胞存活和功能。
Methyl gerfelin inhibits osteoclast differentiation by binding 3 major cellular proteins: glyoxalase 1 (GLO1), sterol binding protein 2 (SCP2), and small glutamine-rich tetratricopeptide repeat containing protein A (SGTA). Methyl gerfelin is a potent GLO1 inhibitor related to the flavonoid class.
体外研究：
Methyl gerfelin (0-30 μM; 72 h) 抑制破骨细胞形成，IC50 为 2.8 μM，有效浓度下不影响成熟破骨细胞存活和功能。
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