产品
编 号:F759380
分子式:C14H14N4OS
分子量:286.35
产品类型
结构图
CAS No: 63932-07-0
联系客服
产品详情
生物活性:
Anti-inflammatory agent 11 (compound 16) is a potent antimycobacterial and anti-inflammatory agent. Anti-inflammatory agent 11 inhibits Mtb H37Rv and M299 growth, with MIC50 (minimum inhibitory concentration 50%) of 1.3 and 6.9 μM, respectively. Anti-inflammatory agent 11 inhibits NO through the suppression of iNOS expression, and also inhibited the production of TNF-α and IL-1β. Anti-inflammatory agent 11 can be used for tuberculosis (TB) research.
体外研究:
Anti-inflammatory agent 11 (compound 16) is active in the reduction of accumulated nitrite, with an IC50 of 64.8 ± 1.0 μM.