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编 号：F759334
分子式：C9H10NNaO4
分子量：219.17
分子式：C9H10NNaO4
分子量：219.17
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CAS No: 63302-01-2
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L-DOPA (Levodopa) sodium is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA sodium can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA sodium has anti-allodynic effects, and can be used for Parkinson's disease research.
体内研究：
L-DOPA sodium (20 mg/kg; orally) reduces Rotenone-induced motor dysfunction.L-DOPA sodium (0-100 mg/kg; orally) reverses tactile, cold and heat allodynia in neuropathic rat without any side effect in sprague-Dawley rats.Animal Model:C57BL/6J mice (7-week-old)
Dosage:20 mg/kg
Administration:Orally
Result:Reduced Rotenone-induced motor dysfunction.
Animal Model:Sprague-Dawley rats
Dosage:10, 30, 50, 70, and 100 mg/kg
Administration:Orally
Result:Reverses tactile, cold and heat allodynia in neuropathic rat without any side effect.
L-DOPA (Levodopa) sodium is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA sodium can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA sodium has anti-allodynic effects, and can be used for Parkinson's disease research.
体内研究：
L-DOPA sodium (20 mg/kg; orally) reduces Rotenone-induced motor dysfunction.L-DOPA sodium (0-100 mg/kg; orally) reverses tactile, cold and heat allodynia in neuropathic rat without any side effect in sprague-Dawley rats.Animal Model:C57BL/6J mice (7-week-old)
Dosage:20 mg/kg
Administration:Orally
Result:Reduced Rotenone-induced motor dysfunction.
Animal Model:Sprague-Dawley rats
Dosage:10, 30, 50, 70, and 100 mg/kg
Administration:Orally
Result:Reverses tactile, cold and heat allodynia in neuropathic rat without any side effect.
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