产品
编 号:F759290
分子式:C22H38N2O
分子量:346.55
产品类型
结构图
CAS No: 627052-25-9
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产品详情
生物活性:
SQ609 is a lead compound from a library of dipiperidines. SQ609 inhibits more than 90% of intracellular bacterial growth at 4μg/ml and is toxic to these cells. SQ609 displays a potent antitubercular activity .
体内研究:
SQ609 (10 mg/kg; intravenous injection) completely prevents weight loss in the Mtb-infected animals and prolongs the therapeutic effect following drug withdrawal for another 10-15 days.Animal Model:TB susceptible mice (C3H/He)
Dosage:10 mg/kg
Administration:I.v.
Result:Prevented weight loss in the Mtb-infected animals and prolonged the therapeutic effect following drug withdrawal for another 10-15 days.
体外研究:
In Mtb-infected macrophages in vitro, SQ609 inhibits more than 90% of intracellular bacterial growth at 4μg/ml and is toxic to these cells.