产品
编 号:F758938
分子式:C11H8FN3O3
分子量:249.2
产品类型
结构图
CAS No: 56563-17-8
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产品详情
生物活性:
PluriSIn #2 is a selective transcriptional inhibitor of topoisomerase II α (TOP2A). PluriSIn #2 is a compound that selectively eliminates undifferentiated human pluripotent stem cells (hPSCs).
体外研究:
PluriSIn #2 (20 μM; 12 hours) treatment reduces TOP2A expression at the protein level.A 24h exposure of PluriSIn #2 (20 μM) is sufficient to induce massive cell death in hPSCs, but doesn’t affect the viability of various other cell types derived from them.