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编 号：F758824
分子式：C8H6N4NaO5
分子量：261.15
分子式：C8H6N4NaO5
分子量：261.15
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CAS No: 54-87-5
产品详情
生物活性：
Nitrofurantoin sodium is a potent and orally active antibacterial agent. Nitrofurantoin sodium acts as an antibiotic. Nitrofurantoin sodium can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections.
体内研究：
1.19Nitrofurantoin pharmacokinetic effects in SD Rats. Parameters10 mg/kg p.o.2 mg/kg i.v.
AUC0-720 (μg/mL?min)306
AUC0-120 (μg/mL?min)90.3
AUC0-∞ (μg/mL?min)34491.5
Cmax (μg/mL)1.01
CL/F or CL (ml/min/kg)31.022.7
t1/2 (min)16623.6
Bioavailability (%)60.1
体外研究：
Nitrofurantoin sodium (0-512 mg/L; 8 h) treatment inhibits the growth of E. coli isolates.
Nitrofurantoin sodium is a potent and orally active antibacterial agent. Nitrofurantoin sodium acts as an antibiotic. Nitrofurantoin sodium can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections.
体内研究：
1.19Nitrofurantoin pharmacokinetic effects in SD Rats. Parameters10 mg/kg p.o.2 mg/kg i.v.
AUC0-720 (μg/mL?min)306
AUC0-120 (μg/mL?min)90.3
AUC0-∞ (μg/mL?min)34491.5
Cmax (μg/mL)1.01
CL/F or CL (ml/min/kg)31.022.7
t1/2 (min)16623.6
Bioavailability (%)60.1
体外研究：
Nitrofurantoin sodium (0-512 mg/L; 8 h) treatment inhibits the growth of E. coli isolates.
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