产品
编 号：F758581
分子式：C158H263N49O50S3
分子量：3745.27
分子式：C158H263N49O50S3
分子量：3745.27
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规格
价格
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结构图
CAS No: 507289-11-4
产品详情
生物活性：
Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research.
体内研究：
In vivo in normal canines, Cenderitide (10, 50, and 100 ng/kg) is a potent cGMP stimulator that has renal enhancing and cardiac unloading effects, with less reduction of blood pressure.
体外研究：
Cenderitide has antiproliferative, anti-fibrotic, and anti-hypertrophic properties.
Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research.
体内研究：
In vivo in normal canines, Cenderitide (10, 50, and 100 ng/kg) is a potent cGMP stimulator that has renal enhancing and cardiac unloading effects, with less reduction of blood pressure.
体外研究：
Cenderitide has antiproliferative, anti-fibrotic, and anti-hypertrophic properties.
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