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编 号:F758552
分子式:C45H50N4O12S3
分子量:935.09
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生物活性:
Shishijimicin B is an active compound of the enediyne class. Shishijimicin B shows extremely potent cytotoxicity with IC50 values of 2.0-3.3 nM. Shishijimicin B has antitumor activity and can be used for the research of cancer. Shishijimicin B is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

体外研究:
Shishijimicin B (compound 2) has high cytotoxicity for 3Y1, Hela and P388 cells with IC50 values of 3.1 nM, 3.3 nM and 2.0 nM, respectively.
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