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编 号:F758489
分子式:C17H14N4O
分子量:290.32
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生物活性:
OX01914 is a water-solube and permeable utrophin modulator (upregulates utrophin protein levels), with an EC50 of 20.5 μM. OX01914 can be used in study of duchenne muscular dystrophy (DMD).

体外研究:
OX01914 (0.1, 10, 40, 50 μM; 24 h) upregulates utrophin mRNA in LUmdx and (30 μM; 24 h) H2K mdx myoblasts.OX01914 (1, 3, 30; 24 h) upregulates utrophin protein levels in human DMD muscle cells.
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