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编 号:F758402
分子式:C17H20N2S
分子量:284.42
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生物活性:
Anti-inflammatory agent 15 (compound 29) is a potent antimycobacterial and anti-inflammatory agent. Anti-inflammatory agent 15 inhibits Mtb H37Rv and M299 growth, with MIC50 (minimum inhibitory concentration 50%) of 2.3 and 7.8 μM, respectively. Anti-inflammatory agent 15 inhibits NO through the suppression of iNOS expression, and also inhibited the production of TNF-α and IL-1β. Anti-inflammatory agent 15 can be used for tuberculosis (TB) research.

体外研究:
Anti-inflammatory agent 15 (compound 29) is active in the reduction of accumulated nitrite, with an IC50 of 71.7 ± 1.1 μM.
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